[DesaiAshu]

Adjacent medicines have seen major improvements: eg Ketamine was a significant improvement from PCP (notably, less psychosis and safe enough to use off the battlefield / with children)

“Removing the worst and most fatal danger” is a laudable goal with Fentanyl given the absurd rate of ODs

[at-w]

As have the opioids buprenorphine and Suboxone (buprenorphine/naloxone), which are genuinely useful treatments for addiction and have much lower risks of abuse.