No, it cannot. It can sort of compile some animations (with the libary EaselJS), but you have to use javascript instead of actionscript - but it is really not the same like it was in flash. Basically it does not work for me and I abandoned Adobe Animate and still looking for replacement of the lost Garden of Flash Utopia.
Flash required a browser plugin to work. It was handling video and 3D animation a decade before the <video> and <canvas> elements were added to the HTML5 spec.