Wireguard to where? Another ISP/VPN that can also sell/MITM your traffic just as well? Non-residential exit IPs are also very often blocked by many websites.
Residential ISPs are well setup for monitoring home traffic (and legally required to in most places). A VPS in a different jurisdiction is vastly less likely to be good at it.
You occasionally get blocked, but not that often if you can putup with a few more captchas. Can't remember it ever being more then a minor inconvenience and well worth this cost.
My home internet is 5G, and many, many websites are blocked or have infinite captcha loops... even well-known sites. Etsy is blocked. Reddit/Discord/Locals is blocked. Archive.is only captcha loops. Even libera IRC is blocked. Trying to buy products online often gets the order flagged or canceled as a potential bot or VPN. IPs are rotated often so I unfortunately have to share bad-reputation IPs with people who keep the addresses on global blacklists like DroneBL that are used by many sites. Even 4chan blocks most of the IPs I get because other people post CP from there.
Trying to use a VPS/cloud IP or well-known VPN provider, the experience for me is just as bad or worse.
For some, the issue is a lot worse than you think.