[mmooss]

> Then how does ozempic, whose primary mechanism of action is to decrease appetite, work for obese people?

That is a very interesting question.

> your body is not magic.

But it is a complex, highly adaptable system. The simplistic formula of calorie input = output is highly misleading.

> If you feed it a sufficiently low amount of calories

Sure, if you starve yourself, you'll start transitioning to dust pretty soon.

[indecisive_user]

Somewhere between obese and dust you'll eventually hit a healthy weight.

https://pmc.ncbi.nlm.nih.gov/articles/PMC2495396/

[mmooss]

That's a report on one person under direct medical supervision. The general consensus, afaik, is that starving yourself doesn't work, at least not more than short term - the weight comes right back.