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by JumpCrisscross 157 days ago
> how do you ever stop?

By not taking it.

> Seems like GLP-1's are not a cure but treat the symptoms

This goes against all of the evidence around rebound, improved diet and exercise after folks have lost weight, et cetera.

1 comments

It is mixed. It can be a cure for some people. Last time I looked my impression it seemed like about half the people has only moderate rebound or less.

You have a lot of results that look like this, with an average bounce rebound of 2/3s of the loss.

https://pubmed.ncbi.nlm.nih.gov/35441470/

However, detailed analysis usually shows a bimodal distribution, with people who maintain or even lose more, and those that go back or even gain relative to baseline.