[OutOfHere]

I fully understand that various articles, even peer-reviewed ones, can be bogus, and some reviews can be bogus too when they demonstrate an unfair bias in selecting articles. Journal managers too can be altogether apathetic. Even so, it has been my experience that reviews over the long term converge to the truth.

As for individual studies, if a study is important, it often gets tested by others, although sometimes it doesn't, and then it's a decision-theoretic play.

Cochrane in my estimation examines things from very narrow angles, and this can miss wide-ranging applicability to the real world.