It's not exactly a template-meme, or whatever low-effort memes are called now (the ragefaces, the reaction gifs, the deep-fried slop).
I think something like xkcd comics or something similar has always been received well by the community. Given that it's a high-effort piece of content as a digital painting, I think it should be ok - or at least not treated like it's in the same bucket as memes.