[jermaustin1]

I wouldn't trust that a nurse or doctor that is bedside to flag that either, though. Hospitals are woefully understaffed, and while they will do there best, we are all just humans.

My wife's grandmother was killed by a second dose of metformin (well kidney failure after a second dose) because the attending that administered the first dose left the room, planning on coming back a moment later, when the next round nurse came in, they noticed the does hadn't been administered (wasn't in the chart), ordered another dose, and injected it.

There were multiple layers that should have prevented that. The prescription shouldn't have been filled for a second time without someone noticing. The first doctor should have filled in the chart before leaving. And the pharmacist should have noticed that it had already been requested.

Too many patients, too few doctors, and with Epic, too many button clicks.

[skeptical_md]

I am very sad to hear that your grandmother died as a result of a medical error, but the details of the story as you remember them aren’t quite plausible.

1) Metformin is not available in an IV formulation 2) Metformin itself is not nephrotoxic

It certainly is believable that a medical error caused kidney failure but it is very unlikely to have been caused by an incorrect second IV dose of Metformin.

[daveguy]

I expect GP mistook metformin-associated lactic acidosis in a patient with kidney disease as something metformin-caused. A separate but coincident IV misadministration could be an exacerbating factor. It would have been a rare case, but a plausible explanation for the misunderstanding.

Metformin is relatively kidney safe and not administered by IV. Thank you for clarifying that for anyone that may currently on or considering Metformin. It would be great if medical professionals were infallible communicators and had time to verify understanding, but they are human and we need more doctors and less time-pressure by profit extracting private equity.

Disclaimer: I am not a doctor.

[BobaFloutist]

Also even when medical professionals communicate flawlessly, they're communicating to non-professionals who will necessarily encode their understanding in an imperfect mental model that will likely degrade over time.

[jermaustin1]

I'll defer to your expertise. I wasn't there, and just sharing what aunt was "told".

[cratermoon]

I don't see any mention of IV in the OP comment.

[moioci]

It says the second dose was "injected."

[cratermoon]

yeah, you can do that with needle and syringe.

[cratermoon]

Oh absolutely, especially in an emergency. I mentioned the other scenario because when I've told this story before people have been skeptical that a bedside provider could make that kind of error.

[malcolmgreaves]

Damn, sorry to hear that a nurse killed your grandma :(