[tyleo]

This reasoning is not flowing through for me. It feels like you are saying:

1. There is an off ramp for TRTs but some people have, “true permanently lowered levels of hormones.”

2. For GLP-1s, “there is no off-ramp, but the only effects I’ve noticed are a return to my baseline.”

To clarify my original post, I consider the ability to return to baseline to mean there is an off-ramp and permanently impacted to mean there is no off-ramp.

[financltravsty]

1. Yes, but that is not -- to the best of my understanding-- because of TRT itself

2. Yes

There is no "off ramp" for GLP-1s in my experience, because the off ramp is so insignificant to not worth a mention. You just don't take another dose after a week has passed from the previous one, and you're back to baseline. Same way there is no off ramp on taking aspirin -- just don't take it.