[djcb]

I wrote an emacs-based e-mail client "mu4e"; see e.g. http://emacs-fu.blogspot.fi/2012/08/introducing-mu4e-for-ema...

Its user-interface is a bit mutt-influenced, but it's fully query-based and very fast, and of course you can extend it using elisp. A fairly young project, but it's near-fully documented, and the manual has instructions on how to set things up with Gmail.

[philjackson]

I'm going to dive in here and give a huge thumbs up to mu4e. I spent a chunk of time with Gnus and Wanderlust and both feel so much slower. I can't make the switch yet because I'm too lazy to research how to get the multiple mailbox/index configuration I have with mutt (if it's possible?) but hopefully will soon.

Really appreciate the work, djcb.

[djcb]

There can be only one database (index) per mu4e/emacs instance, but you can store multiple maildirs in one database though, and there's support for multiple accounts (esp. in the upcoming 0.99; there are some recent ML-threads about this).

[pnathan]

How does that play out vs. gnus? I have messed around with gnus a bit but don't feel 100% happy with it.