[walletdrainer]

It is worth also considering the far stronger bias against psychedelics that exists in society as a whole.

LSD is illegal, and in most countries considered one of the most dangerous drugs despite being completely harmless from a physical perspective.

[otherme123]

I don't use drugs, but the LSD situation is crazy: is well down in any rank of harm (both to user and to others). The alleged harm has been proved fabricated (people getting blind for staring at the sun) or incredibly overstated (suicides while tripping). Is way less dangerous than tobacco or alcohol, and has next to zero addiction. Their users praise the experience, and some studies show potential medical use. Yet is furiously prohibited, deviled and prosecuted.

We were having a debate among friends when a couple of people said they took MDMA once, and some of the most obviously alcoholics (drunk twice a week) went to their yugular calling them junkies and "irresponsible" because drugs fry your brain.

[Xmd5a]

MDMA fries your teeth. Gave in to 1/5th of a dose with people I was partying with, received one year of tooth-grinding. Never again.

Classic dental study: 89% of ecstasy users reported clenching or grinding; 60% had tooth wear into dentine vs 11% of non-users. https://pubmed.ncbi.nlm.nih.gov/10403088/

ChatGPT: “One pill, one year of grinding” – biologically plausible as a trigger, but not a universal rule.

"I think that MDMA, unlike other drugs, is potentially much more neurotoxic and dangerous than any drug that has comparable effects, like hallucinogens for example, for which we haven't shown long-term alterations. MDMA is therefore a special case. It's difficult to give recommendations for use. It's better not to take it regularly, and if someone asks me, in my opinion, I would say it's better to keep your distance from this drug so as not to run any risks."

Source: Franz X. Vollenweider in 2005, Director Neurophenomenology of Consciousness, Zürich University: https://www.youtube.com/watch?v=RnptUdyDUKI&t=1810

[marknutter]

Wear a mouthguard.

[idiotsecant]

Are you telling me you've never met an old LSD abuser whose brain was fried like an egg? LSD can also trigger legitimate lifelong psychotic states in some people.

There is a big difference between 'generally not harmful in very small singular doses' and 'all harm is fabricated'.

[AngryData]

Ive seen people with fried brains from copious amounts of drug abuse taking everything under the sun that will also sometimes take LSD. Ive never seen someone who only takes psychodelics like LSD and mushrooms, even heroic amounts, have any cognitive problems from it.

[walletdrainer]

> Are you telling me you've never met an old LSD abuser whose brain was fried like an egg?

I’ve known old LSD abusers with fried brains but never seen a LSD abuser go from non-fried to fried brains. Correlation is not causation, but it could be.

> LSD can also trigger legitimate lifelong psychotic states in some people.

These statements should be accompanied by the necessary caveat that just about anything can trigger psychotic states in people prone to psychosis.