[EnPissant]

Does it matter if the pre-wash removes 40% of the fat and the main wash removes the last 60% or if instead the pre-wash removed 20% and the main wash removes the last 80%?

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Yes, the pre-wash clears away the water from that cycle much faster than the main wash, so the cleaner the main wash water is in the beginning, the more effectively it can clean.

[EnPissant]

You are describing something like 20% to 95%.

I am talking about 20% to 100%.