That's really not true though. The downstream processes after biosynthesis will have steps like "lyse all the cells open" and ,"definitely and thoroughly kill them and the off target proteins".
Like you're going to do a lot of very specific, biotoxic things.
It has water as the solvent so plenty of techniques here that dont involve toxic things such as rapid heat pasteurization, as is done in milk processing. Also see centerfugation, crystalization, filtration, etc. You can lyse all cells with shear force easily by mixing excessively fast.
Like you're going to do a lot of very specific, biotoxic things.