[reinhardt]

To make matters worse, there are no less than three Python-like options in the .NET world: IronPython, Boo and Cobra. With such fragmentation C# will probably stay the only game in town for a long time.

EDIT: Apparently Boo hasn't been updated for almost a year.. sad. Oh well, that leaves two choices then.

[1] http://dist.codehaus.org/boo/distributions/

[whiletrue]

Python syntax is just one aspect of Cobra. There is also nil-checking, contracts, and easy syntax for testing.