[zepearl]

To fix stuttering I had to disable compositing in the window manager (Xfce on Linux Mint, nVidia proprietary with AMD CPU).

[nmz]

And there's also pulseaudio, which I had to run in some games with PULSE_LATENCY_MSEC=90 %command%, other games you can only run in lutris, other games you can't even minimize it or it will mess up with the screen entirely.