[R_D_Olivaw]

While I can't speak to these substances, regarding the temporariness of it:

Irrespective of whether or not the effect, or lasting effects, dwindle and can thus be considered "temporary", there's something too be said about the act of the reset itself.

That is, whether or not the effects feel like they're fading, the memory of what it was like when it was new is still a massive data point and can be recalled.

In short, you can still remember that feeling of the reset and recall a time when your brain felt new and refreshed.