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by ml_basics 235 days ago
The graph at the beginning showing the cost of sequencing over time falling faster than Moore's law stops in 2015. Would love to see how things have progressed since then. Casually googling i only saw plots up to 2021 but looks to me like progress is now slower than Moore's law since ~2015. Maybe things will change when Nanopore gets more reliable
2 comments
dust42 235 days ago
The graph also only starts in 2001. I worked as a student at the EMBL (European Molecular Biology Laboratory) in the bio-physics instrumentation group in the mid 90ies. The lab group was developing prototypes of thin-film electrophoresis DNA sequencers. Pharmacia Biotech then bought some of the tech and brought it to market. AFAIR at that time it were some of the fastest sequencers but we are talking of low 100s of base pairs per day.
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mfld 235 days ago
The NHGRI updated these plots for years. Sad to see that there is no update since 2022, presumably due to lack of funding.

The sub-$100 genomes could be in reach within the next 5 years, from what I have seen.

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