Just for clarification, you mean machine learning rather than ML the language, right?
(I ask because this discussion is talking about both the genetic algorithms and Coffeescript).
Hmm... maybe some sort of GPS application that took into account current road conditions -- length of time stopped at traffic lights, performance characteristics of the current vehicle (velocity and acceleration away from lights, etc).
At one time there was talk of making the air traffic control system distributed rather than centralized. The win there is that 1) each aircraft only has to worry about the other aircraft that near enough to interfere and 2) if the control system goes out in one aircraft, the systems in the other aircraft can compensate. By contrast the centralized system has to watch all the aircraft in a large chunk of airspace, and if it goes out, well...
This is sort of what Google is doing with their self-driving cars, I think (that's just my impression -- I haven't looked into it in detail).