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by westurner 244 days ago
Other potential cancer treatment methods that 2.5pro - a different model than is referenced in the article - has confirmed as potentially viable when prompted by an amateur cancer researcher:

- EPS3.9: Polysaccharide (deep sea bacterium sugar, fermentable, induces IFN-1) causes Pyroptosis causes IFN-1 causes Epitope Spreading (which is an amplifying effect) causes anti-cancer response.

- CPMV; Cow-Pea Mosaic Virus (is a plant virus that doesn't infect humans but causes an (IFN-1 (IFN-alpha and a lot of IFN-beta)) anti-cancer response in humans. Cow Pea consumption probably used to be even more prevalent in humans before modern agriculture; cow peas may have been treating cancer in humans for thousands of years at least.)

I emailed these potential new treatments to various researchers with a fair disclaimer; but IDK whether anything has been invested in developing a treatment derived from or informed by knowledge of the relevant pathways affected by EPS3.9 or CPMV.

There are RNA and mRNA cancer vaccines in development.

Without a capsid, RNA is destroyed before arrival. So RNA vaccines are usually administered intramuscularly.

AFAIU, as a general bioengineering platform, CPMV Cow-Pea Mosaic Virus could also be used like a capsid to package for example an RNA cancer vaccine.

AFAIU, CSC3.9 (which produces the "potent anti-cancer" EPS3.9 marine spongiibacter polysaccharide) requires deep sea pressure; but it's probably possible to bioengineer an alternative to CSC3.9 which produces EPS3.9 in conditions closer to ambient temp and pressure?

> Would there be advantages to (CPMV + EPS3.9) + (CPMVprime + mRNA)? (for cancer treatment)