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by JumpCrisscross
251 days ago
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> its about to push this in a moment The point is acetaldehyde metabolism is at the heart of your question: Why do some people flush red with alcohol. Reading the first reference on Wikipedia's article about alcohol flushing [1][2] would have generated, I believe, more understanding about the biochemistry involved. (And the fact that ALDH2 deficiency simply exacerbates something we all do--acetaldehyde is a big part of what causes hangovers.) What that would not have done is demonstrate (a) a genuinely interesting way to "step through" a physical system and (b) the ease with which a biochemist might be able to do so. As a hack and a project and a mode of communicating a model, I love this. Where I'm objecting is in pitching it per se as a mode for understanding a phenomenon, in this case, "what ALDH2 deficiency is." [1] https://en.wikipedia.org/wiki/Alcohol_flush_reaction#cite_no... [2] https://pmc.ncbi.nlm.nih.gov/articles/PMC2659709/ |
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