[iEchoic]

The "standard" strategy is to play GTO (game theory optimal). There are solvers out there (like GTO Wizard) that show you the "optimal" play for every situation, which is used as a baseline, and then players deviate to exploit specific player tendencies.

GTO trees are far too complex to fully memorize, so nobody can play perfect GTO. But you can do a lot of solver work to get reasonably close.

[brightball]

I won a tournament on a cruise against a guy who I think was doing this. He was one of the people at the table who had a consistent tell and that helped me beat him heads up.

[noitpmeder]

What was the tell? And separately, why do you suspect he was playing GTO?

[brightball]

Maybe not GTO specifically, but I got the impression that he was playing the math and doing it well (especially since it came down to the two of us at the end).

The tell was a very common one. Anytime he liked what he saw, either hole cards or on the flop, he would quickly glance at his chip stack (thinking about a bet). Probably didn't even realize he was doing it. When it got to head to head, if he glanced at his chips...I'd fold early. If he didn't, I'd bet into him until he eventually folded.