[goku12]

The article I cited is from 2022. At that time, the principal scientist had left the academia and was working to commercialize it. So I'm guessing it's still within your decade threshold? Besides, perhaps that threshold should be longer under the current circumstances. One of the greatest medical advancement of the recent times is the mRNA vaccine technology. But it's true origin is in the 1970s. They were solving numerous related problems in the meantime, though it could have been finished sooner had someone invested in it as intensely as they did during the pandemic.

[hinkley]

Looking at bibliographies, it seems like a lot of the research for decellularization was 2011, 2013, and a handful after. So they were still working on getting a clean substrate while working on how to fill it back in.

It’s a big problem, but still seems like they’re swinging for the fences when they could save people in the short term while working on organs.

[goku12]

Interesting! I just remembered that there is another team that's working on plant based scaffolds (cellulose scaffolds from leaves like spinach) [1]. This one is from 2017. So I'm guessing that the interest in the technology hasn't waned yet. I also wonder if any biocompatible scaffolds can be 3D printed, rather than having to decellularize the available ones.

[1] https://arstechnica.com/science/2017/03/spinach-leaf-transfo...