[teslabox]

There is no row over Tylenol: there are comments on HN going back for at least 13 years how this drug would probably not be approved if an application was submitted today.

I've joked that if you're an old person trapped in a nursing home, one strategy to get yourself out of there is by cheeking a bunch of tylenol until you have enough, then taking them all at once. 4000mg/day starts to damage the liver. 10,000 mg can lead to liver failure. A pharmacist told me that Tylenol-induced liver failure is not a very pleasant way to die.

There are 2016/2017 tweets by @Tylenol about how the drug shouldn't be used during pregnancy: https://x.com/tylenol/status/839196906702127106 https://x.com/tylenol/status/773897927420841985

This thread was started by someone who commented on how Eric Engstrom (the co-creator of DirectX) accidentally euthanized himself with Tylenol: https://news.ycombinator.com/item?id=25424258

FDA: Acetaminophen one of the most dangerous drugs on the market, March 26, 2023: https://news.ycombinator.com/item?id=35309904

"[...] we can get away with things that we wouldn't be able to get away with nowadays. There's a lot of stuff that's like this; for instance, paracetamol/Tylenol would probably not be approved if it was introduced now because it's really easy to accidentally overdose on." August 6, 2012: https://news.ycombinator.com/item?id=4347943

[add-sub-mul-div]

If the suggestion is that it should be outlawed, there's no reason to punish the vastly outnumbering population who can follow directions and take it safely. You can also accidentally kill yourself in a car every time you get into one if you're not careful. Many actually do.

A pregnant woman who ignores symptoms during pregnancy is putting the fetus at greater risk than one who follows her doctor's suggested treatment, which may include acetaminophen.

[teslabox]

> there's no reason to punish the vastly outnumbering population who can follow directions and take it safely.

If you take two pills of extra strength Tylenol (2x500mg) every six hours as directed by the instructions, you’ve reached the threshold for liver injury.

Around 50,000 people a year (U.S.) visit the ER for having poisoned themselves with acetaminophen. A lot of people harm themselves without realizing it. I warned a friend about her Tylenol habit, which helped her connect “dizziness” to the Tylenol she’d just taken.

[Dylan16807]

So, it is easy to screw up.

But the second line of the instructions is a limit of 6 pills per 24 hours.

[misnome]

And “178,000 people die from excessive drinking each year”, so, prohibition?

> which helped her connect “dizziness” to the Tylenol she’d just taken.

Anecdotal bullshit

[Dylan16807]

I don't understand your comment at all.

There is a row, and it's about something extremely different from liver failure.

And even if it wasn't about something different, you can have a row about a known problem.

[asacrowflies]

It's not in good faith so no point in trying to argue with these types. It's alot lot like the ivermectin thing during covid.

[teslabox]

I’m not sure what you mean. This submission had fallen to the second page, without any substantial comments.

Are the HN comments cautioning about Tylenol now invalid because President Trump shared the same sentiments?

Defending Tylenol seems like an odd hill to plant your flag on.

[Larrikin]

He's a Tesla booster. You're wasting your time

[Bender]

A pharmacist told me that Tylenol-induced liver failure is not a very pleasant way to die.

That is putting it mildly. It is arguably one of the most painful ways to self delete.

[sorokod]

An example lethal dose table here.

https://en.m.wikipedia.org/wiki/Median_lethal_dose

Aspirin and Caffeine are lethal, so are Capsaicin and water. What is your point?