[tomxor]

> The underlying mechanisms (reduced inflammation, improved fat distribution, better metabolic health) aren't unique to that group

Those are causes, you can't just invert it (again) and call them mechanisms for anti-aging... Those things are side effects of obesity and diseases causing obesity, there is no evidence or reasonable basis here to suggest there would be any "anti-aging" effect in healthy people without those problems.

Similarly "Ozempic shows anti-gravity effect in humans!#11"... assuming you have unhealthy excess fat to lose.

[edmundsauto]

Cause and effect in the body are intertwined with some very clear and mostly not understood feedback and feedforward loops.

[cthalupa]

Except the post they responded to specifically called out HIV-associated lipohypertrophy and the post you are responding to pointed out that the issues being tackled are not unique to HIV-associated lipohypertrophy.

More than 70% of Americans are overweight. That's a pretty overwhelming majority. Most of the Western world and significant portions of the Eastern world are trending in the same direction.

The point is that this can be generalized to a whole lot of people, not just those with HIV.

And there are other causes of inflammation besides just being overweight, and the GLP-1s reduce inflammation basically immediately, even with no weight loss.