[King-Aaron]

The American Tobacco Company marketed cigarettes for women's weight control in the 1920's. Lucky Strikes 'Reach for a Lucky" campaign was a big example of this as well, although they marketed it as an appetite suppressant rather than simply a miracle weight loss cure.

[cik]

Keeping in theme, Ozempic specifically has already been marketed off label as an appetite suppressant, rather than a pure weight loss drug. That's a more modern construct in its brief history.