The Scarlett should be USB class-compliant. I've got a Motu 2i2o DAC that I've been using on Linux for 3 years now, and before that used a Behringer U-Phoria without issues.
It is class-compliant - but to this day, I've never figured out, how to use the multitrack out with Pulse. The widget shows all the outputs and testing individual outs works, but Reaper duplicates the sends, so the outputs overlap. Works with JACK though, but JACK is just strange. Also no control software (aside from one open-source thingy that looks awful), so any change requires reboot to Windows or VM passthrough.