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by im3w1l 334 days ago
Cells can exchange mitochondria so in theory it might be possible to flood the body with healthy mitochondria and get them to slowly take over.
3 comments

I would expect that to activate the immune system. "the unique components of mitochondria, when exposed, reveal their prokaryotic history and are recognized as foreign by innate immune receptors triggering an inflammatory response." https://pmc.ncbi.nlm.nih.gov/articles/PMC6218307/

Maybe if you suppress the immune system, introduce working mitochondria, and then stop taking the immunosuppressants, any mitochondria that are still outside cells get cleaned up and the ones that got absorbed are shielded and can do their job.

Maybe we can find some way to deliver mitochondria right into the cells.
Mitochondrial health is definitely going to be a big theme in the coming years.
> it might be possible to flood the body with healthy mitochondria and get them to slowly take over

it's not possible, these are organelles that are too big to be taken up by your cells, unless you can magically teleport them somehow to each cell