[pxc]

If Python devs/users had to actually use all pure Python libraries, no C bindings or Rust bindings, no RPC to binaries written in faster languages, it would get dropped for a ton of use cases, absolutely including its most prominent ones (machine learning, bioinformatics, numeric analysis, etc.).

[cestith]

It would probably especially include those before most others. The best thing about Python IMO is the FFI and the ecosystem built around it.