The study mentions they administered 30 milligrams of psilocybin for 70 kg of body weight. Does anybody know how many grams of dried mushrooms that is equivalent to, roughly?
A good ballpark for dried shrooms is roughly 1% psilocybin by weight of dried shroom, so about 3g. That said, it's going to vary a lot shroom to shroom, genetic to genetics, and species to species. Could be as high as 6g for more mild strains and as low a 1g for something like pan cyans.
That is the problem with clandestine pharmacy by Florida man, as people may get the wrong dose or a mixture of various other poisons like arsenic (see dark web article.)
When ready, please talk with your doctor first. =3
I've been doing some recent research and testing, and here's what I have found: I'm talking about the "Penis Envy" strain, which is quoted as being ~30% more potent than typical. 2g is the edge of where I start getting visual artifacting, and only sometimes. 3g, which I have not tried, was quoted as being towards the upper end of a "theraputic dose", and 6g as the upper end of a recreational dose. Some friends with much more experience consider 1g to be microdosing, FWIW. 0.25g I can't feel at all. .5g I start to feel some euphoria and 1g to 1.5g I start to feel "high" but with no noticeable psychedelics or just minor visual artifacting when I'm reading.
I don't really have anxiety or depression. I do have a fairly high stress family life, wife and kiddos have lots of issues. A few weeks ago I had 2g on an empty stomach on a Sunday and I just listened to music for ~4 hours and it was like I had a vacation. I hadn't enjoyed listening to music so much for 20-30 years. Also, I seem to feel kind of sleepy when I'm trippy, but afterwards I'm wide awake for 4-5 hours. So evening dosing is best avoided.
It's kind of great, for me personally, living in a state where it has been decriminalized.
"[...] psilocybin converts to psilocin in the body at roughly a 1:1 ratio by active effect [...]
Psilocybe cubensis (most common): Contains about 0.5-1.0% psilocybin by dry weight. Since psilocybin converts to psilocin in the body at roughly a 1:1 ratio by active effect, 30mg of psilocin would be equivalent to roughly 3-6 grams of dried P. cubensis.
Psilocybe semilanceata (liberty caps): Much more potent at 1-2% psilocybin content, so you'd need only about 1.5-3 grams dried.
Psilocybe azurescens: Even more potent at 1.5-2.5% psilocybin, requiring roughly 1-2 grams dried.
Important caveats:
- Individual mushrooms within the same species can vary by 3-5x in potency
Growing conditions, harvesting time, and drying/storage methods all affect potency
- The caps are typically more potent than stems
- Fresh vs. dried makes a huge difference (fresh mushrooms are ~90% water)"
Have to note that the paper is from 2016; for those really interested, it's good to read recent review papers.
I learned from an episode of "The Studio" that by "an eighth" you are likely referring to an eighth of an ounce is around 3.5 grams. Dude thought he got really mild shroom laced chocolates ("an eighth of a gram") and much hilarity ensued.