[fc417fc802]

> I don't think I can say that there is much of a pattern between ADHD and overeating, just based on how easily I can predict if someone is overeating or not if I know they have ADHD. That is, it would be a coin toss.

Person you responded to suggested P( overeating | undereating ) as opposed to your P( overeating ). I expect the effects of those two conditions would tend to cancel each other out in observations.

> As seen in studies where people that start lisdexamfetamine (ADHD medication common in the EU) have a huge reduction in actual amphetamine abuse.

Perhaps I misunderstand you but lisdexamfetamine _is_ an amphetamine. That reads like saying that people prescribed an opiate exhibit reduced opiate abuse. It seems either tautological (not abuse because permitted) or obvious (cooperative supervised use reduces bad things happening) or perhaps related to drug safety (A simply being safer to use than B).

[jtrn]

Regarding under- and over-eating: it seems you think I am a simple mathematical average that doesn't factor that in. I stand by my observation, as and observation, not fact.

Lisdexamfetamine is not amphetamine—not chemically, not in terms of its half-life, not in subjective experience, and not in any study that tracks behavioral or long-term effects. At best, it's a prodrug of an enantiomer of amphetamine. You are also mistaken about the study. Reading even the abstract would clear that up for you.

Let me clean up the unnecessary, convoluted language before I answer: Q: Does it stop being called "abuse" once a doctor prescribes it? A: No. The prescription stopped hospitalizations due to amphetamine overdose.

Q: Is it simply safer to use drugs with a doctor's help? A: That was not answerable based on the study's design. It is also not a useful question to ask in this context, since it's comparing apples and oranges. Some of the worst cases of drug abuse are created and maintained by doctors. However, taking drugs collaboratively with a doctor is probably safer on average than getting them from random webpages.

Q: Is this specific amphetamine safer than others? A: Yes, as is the case with any substance we ingest. You can quibble over the details, but beer is safer than hard liquor. Likewise, different medications in the same category or receptor affinity group have different LD_{50} doses (the ratio of the clinically effective threshold to the threshold where 50% of subjects would die).

[fc417fc802]

> it seems you think I am a simple mathematical average

No, I was merely inquiring after what appeared to be a misunderstanding but apparently wasn't.

> Lisdexamfetamine is not amphetamine

Just to clarify, this topic is always needlessly confusing because "amphetamine" is used to refer to both a distinct chemical as well as an entire class of chemicals. Lisdexamfetamine is _an_ amphetamine in exactly the same way that codeine is an opiate (ie a prodrug of).

I'm not sure why you think I'm mistaken about the study nor why you are so condescending about a misunderstanding rooted in terminology. You yourself state that it is about relative drug safety and the study is also quite clear about this so it would seem that we were in agreement all along.

[jtrn]

Because I get triggered when people are illogical while using excessively complicated language and do not try to understand the points being made. Like in this comment, I clearly laid out all the ways I think lisdex != amphetamine. But you are once again answering in an obvious way without engaging my points.

If you look elsewhere in my comments, I have no problem calling myself an idiot when I make mistakes. But I hate the noise that is bad faith arguing concealed in fancy words.