[wincy]

I’ve been on 15mg (the highest dose) of Zepbound for the past six months. As of right this second I’ve lost 74 pounds since September 2024 when I switched to Zepbound after having a terrible experience with Ozempic/Wegovy and gaining from 260-308.

I notice no ill effects, I just had my three month checkup with the doctor and he thinks I’m good on maintenance mode at max dose, I’ve still got about 34 pounds as my total weight loss goal. Really an ideal case.

For my wife on the other hand she just has constant diarrhea which she blames on the drug, and is only on 5mg. She also gets headaches from the medicine. She’s lost only 20 pounds, even though she needs to lose another 120 or so to be “healthy weight”.

However, before she started taking Zepbound she was only able to walk a few hundred feet at a time, because her back hurt so terribly. The anti inflammatory “side effects” she’s experiencing have massively improved her quality of life, even without huge amounts of weight loss.

[malfist]

I'm sorry to hear about your wife's issues with it. My experience was completely the opposite. Since glp-1s slow gastric emptying they've completely ameliorated my IBS-D. It's been marvelous

[stavros]

I'm on 2.5mg and I just got sulfur burps, which, to me, is the worst side-effect of the lot. I've also gotten terrible diarrhea previously, even on the lowest dose, I've started and stopped it around five times. Hopefully fifth time's the charm, but yes, side-effects very much depend on the person. I have friends on 10mg and 15mg and they're fine.