You can indeed. However, if I knew all of the words I would mispronounce, I would have already looked them up! The trouble with mispronouncing words is that often you’re unaware that you’re doing so.
The best one I've heard was from an extremely bright and well-read friend of mine in high school who once pronounced "formaldehyde" like "formal dee-hide" with emphasis on the "dee" syllable.