[mandmandam]

> It seems that pot is about the worst thing that a schizoaffective/schizophrenic person can use.

This isn't entirely true, and it's a dangerous misconception. High THC, low CBD cannabis wouldn't be recommended, but that's exactly what making cannabis illegal selects for.

High CBD, low/zero THC cannabis, on the other hand, will probably be one of the paths to treatment if we ever get over our Reefer Madness and pharmaceutical obsession.

[mikeweiss]

"High CBD will probably be one of the paths to treatment"

On what exactly are you basing that off of? Vibes?

[dakom]

I wouldn't dismiss personal anecdotes any more than I'd dismiss someone claiming they saw something in a reputable journal but can't remember the citation.

In other words, yeah, don't just believe it at face value- but if you have good reason to trust the source, it's worth considering and checking into further.

In this case it's not just one individual but many people saying that THC and CBD are almost opposites if eachother, for example in how they affect anxiety.

Definitely worth proper research imho, could lead to medication that has more of the pros and less of the cons

[mandmandam]

Not trying to be glib, but this is a genuine lmgtfy moment.

https://duckduckgo.com/?t=ffab&q=cbd+antipsychotic&atb=v340-...

[mikeweiss]

No it's not. The poster should have referenced some sources. CBD has been touted as a miracle drug for over a decade now and it seems mostly like a fad at this point. But also it's not well regulated so it's easy for unscrupulous companies and individuals to profit from misleading marketing around it.

[mandmandam]

> The poster should have referenced some sources.

Who, me? ... Why? It's very well known and established that CBD has antipsychotic properties.

And if you don't know, that and don't bring any evidence against it, then why claim otherwise before like, doing a simple search to check your priors?

In any case, I've provided multiple citations elsewhere in this thread, and a whole bunch more come up on the linked search results. This isn't hidden knowledge or anything.

> CBD has been touted as a miracle drug for over a decade now

That's a separate issue.

> it seems mostly like a fad at this point

If you click the link you can see that isn't true.

> also it's not well regulated so it's easy for unscrupulous companies and individuals to profit from misleading marketing around it.

That's a separate issue.

[talentedcoin]

“Dangerous misconception”? Get out of here with that. Cannabis is dangerous for schizoaffective people. Why are people that smoke pot so tiresome about this? Just accept that it’s not good for everyone!

[mandmandam]

> “Dangerous misconception”? Get out of here with that.

I will not.

The demonization of cannabis has led directly to it becoming high THC and low CBD, as I said. It also has lead to it often being tainted with all manner of adulterants, from ketamine to glass beads to plaster dust to worse.

> Cannabis is dangerous for schizoaffective people.

CBD is a leading target of research for it's anti-psychotic properties; and if you don't know this it's a complete mystery to me why you feel entitled to weigh in.

And it's not even the only compound in cannabis that is being investigated; there are others with anti-psychotic and synergistic potential.

> Why are people that smoke pot so tiresome about this?

What if what I'm saying might be true, and you're dead wrong to accuse anyone who disagrees of being a 'tiresome stoner'?

... Because, in fact, it may well be [0].

> Just accept that it’s not good for everyone!

If it's not for you, that's fine; but the wilful ignorance around cannabis over decades has caused far, far more harm than cannabis ever has.

Can you accept that it will may well have a role in treating "psychosis, in general and schizophrenia, in particular" [0]?

0 - https://pubmed.ncbi.nlm.nih.gov/22716160/

[jazzyjackson]

Legal competition had lead to much higher concentrations of THC than was normal in the bad old days of smoking Mexican brick weed, not to mention the pure accessibility of buying 96% THC vapes wherever you go in unlimited amounts as opposed to being happy you could get your hands on an ounce.

[ChrisMarshallNY]

Eh, maybe. I can certainly say that I have "skin in the game." Someone very dear to me suffers from it, and it's difficult to hear theories from folks that don't have as much of a stake.

That's one reason that I have compassion for parents of autistic children, that are vehemently anti-vax. I completely disagree with their stance, but I know what they are dealing with, and the very real fears and stresses that they are under.

[mandmandam]

> it's difficult to hear theories from folks that don't have as much of a stake.

It's not a theory that CBD has anti-psychotic properties. It certainly does, we just don't fully understand why.

My theory is that it will someday be part of treatment plans; and as someone with skin in the game I would hope that you care enough to learn a bit more about it. The comparison to anti-vaxxers with autism in the family is not appropriate here.

[ChrisMarshallNY]

> is not appropriate here

Actually, if the agenda of pushing CBD therapy applies, then it is. I know a number of folks that have autistic children, of various levels, from "nerd," to "wheelchair-bound." Their parents are usually absolute saints, regardless of their political views, or misinformation diets, and live in constant pain; making daily sacrifices that I don't think many folks here, can even comprehend.

We were discussing a serious mental illness, and, as someone that is a caregiver for someone like that, I think that my experience is relevant; just as someone who believes that their child's condition was caused by something that is really a red herring.

The real villains, here, are the people that have secondary agendas (like legalizing drugs, or pushing political agendas), and look at people like us, with very real pain, as nothing but pawns, to be used to push their agenda (Think of the children!).

CBD, like Blockchain, probably has some valid application, but, because it was so unexplored, scientifically, it is currently about 75% snake-oil. We'll find out what it's good for, over time. The same can be said for other drugs, like MDMA, microdose LSD, or psilocybin.

[mandmandam]

CBD has an antipsychotic effect. There's not really any debate on that in the scientific community, and I've already provided a link. That's not part of some sinister agenda to legalize cannabis, it's just stating facts to clear up the misinformation which at this point you are willfully repeating.

> The real villains, here, are the people that have secondary agendas (like legalizing drugs, or pushing political agendas), and look at people like us, with very real pain, as nothing but pawns, to be used to push their agenda

Your assumption that I don't also have personal experience, and a stake, and real pain with this issue is based on what exactly? Did I miss the part where you asked me about my own experience, or does your personal experience trump my own for some reason?

I do, in fact, have all three. That has no bearing whatsoever on the basic fact that CBD has confirmed anti-psychotic potential with particular regard to schizophrenia, as was already linked above.

Finally, there's no secret agenda here - cannabis should be legalized. It's just basic common sense and decency, for all the reasons I've already stated and more. Prohibition doesn't work and we have decades of data proving that beyond any doubt.

Have rates of psychosis shot up in states where cannabis was legalized? No, according to a massive analysis of 63,680,589 beneficiaries followed for 2,015,189,706 person-months [0]. So please, stop with the reefer madness. I'm sorry about your family member but if you want to help people you could really try looking at the data.

[ChrisMarshallNY]

> I do, in fact, have all three.

I don't believe you. If you had, you would have led with it, just like I did. I value people that have skin in the game. Jenny McCarthy is a big fat pain in the ass, but she really does have an autistic kid, is a good mother, and has formed her worldview around that.

> So please, stop with the reefer madness.

WTF? I've never believed that crap in my life. Interesting that it's important to you, that I support that twisted worldview. You've mentioned it a couple of times, so it seems to be something that you're fixated on.

I do, however, have considerable experience with the fallout from drug use. I have spent my entire adult life, helping folks out, who have had their lives shattered by it. There are a small percentage of the population that can't handle drugs, and need help to recover from it. I do my best to help them out, and don't insist that the vast majority of the population change their worldview to fit mine.

Personally, I think that pot should be legal everywhere, including at the federal level (which will basically kill all the "mom and pop" operations out there, so be careful what you pray for). I don't use it, and don't care, myself. That doesn't make me an enemy.

I'd gently suggest that a professional forum, read by many of the most influential people in tech, might not be the best place to be a crusader for drug use.

[mandmandam]

> I don't believe you. If you had, you would have led with it, just like I did.

You really can't imagine someone arguing from scientific research over their own personal experience?

> Jenny McCarthy is a big fat pain in the ass

Again with the autism/vaccines comparison, again missing the point, again doing yourself and your family member a disservice.

> WTF? I've never believed that crap in my life.

You keep repeating the claim that there's no therapeutic value to cannabis. That's madness, my friend, by the very literal definition of ignoring reality.

> don't insist that the vast majority of the population change their worldview to fit mine.

That's exactly what you're doing though? You're insisting that people ignore the research which I've linked multiple times now, and adopt your worldview which is based on vague assertions and claims; and you insist that anyone would argue the same way as you're doing when that's neither true or sensible.

> Personally, I think that pot should be legal everywhere, including at the federal level (which will basically kill all the "mom and pop" operations out there, so be careful what you pray for).

Huh? I can't tell if you're insinuating I'm a drug dealer or what your point is here. I'm certainly not the one who made this debate about whether cannabis should be legal or not; I just pointed out that prohibition made it much more dangerous to consume.

> I'd gently suggest that a professional forum, read by many of the most influential people in tech, might not be the best place to be a crusader for drug use.

As has been pointed out by people above, you're the one on the crusade here. My point, which I've repeated many times now, is that CBD has shown potential to help people vulnerable to psychosis and schizophrenia. I don't know why that triggers you so hard, or why you can't engage with the research which shows that very clearly, but I wish you the best all the same.

[aspenmayer]

> The real villains, here, are the people that have secondary agendas (like legalizing drugs, or pushing political agendas)

The natural state of affairs is silence, as plants don't care about humans. The actual history of plant illegalization is inherently political, and inextricably racist in America due to Nixon.

[mandmandam]

I agree, except that the racism involved with prohibition goes right back to Day 1 with Harry Anslinger [0].

0 - https://duckduckgo.com/?t=ffab&q=harry+anslinger+racism&atb=...

[aspenmayer]

I agree, except that isn’t how you cite sources. What’s the point of that? I know how to search, thanks. I will treat every instance of this kind of “let me Google that for you” whether it has Google or not as a native ad and will flag. Please cite a source, or don’t, but either way, stop shilling.

Thanks.