[bluesign]

Actually if you cannot find "good reasons to not use it" by yourself, usually it is better to "use it"

[caller9]

No that could mean you find the reason 2 months from now as you start hammering toward your solution and reach an impass.

Design your app and determine if MonoTouch supports everything you need to do. Dig around to see if it has any runtime quircks found by others. yaknow research.