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by cess11 364 days ago
With 5-HT2a psychedelic substances you get an immediate, extreme tolerance so unlike ethanol or other common GABA:ergics you won't get that kind of every day abuse and related self harm.

Single dose use is more likely to be harmful with ethanol at a comparable degree of intoxication, it is strongly disinhibitory in comparison, but a particular person might be more sensitive one way or the other.