[user_7832]

I haven’t taken it myself, but I’ve heard of methylene blue being helpful, especially post TBIs or head injuries.

Wrt ibuprofen, I find it can (at times) massively clear out my brain fog. I suspect it’s primarily due to its anti inflammatory effects. The worse my baseline is, the more noticeable its benefits (upto a point, and apparently dose dependent). I often feel inflammation due to less sleep and due to another chronic heath condition, ibuprofen is like wiping a dirty glass or window clean.

I should probably add that I likely have more inflammation than the average person by a significant amount unfortunately, so your mileage may vary, but when I mentioned it to my GP he wasn’t surprised at all at its effects.

[jefozabuss]

Be very careful with these "experimental" (to say in the nicest way possible) things like methylene blue as combining with certain meds like SSRIs could be fatal according to https://pmc.ncbi.nlm.nih.gov/articles/PMC2078225/#:~:text=Mo...

[user_7832]

Yes, serotonin syndrome is definitely a serious risk. From what I understand, it's typically caused by interactions between SSRIs or MAOIs and substances like methylene blue, rather than methylene blue broadly interacting with many compounds. But I agree - caution is essential when dealing with anything that affects brain chemistry.

[AStonesThrow]

More fatal than just taking the SSRIs?

Do they also increase the homicidal ideations?

[IAmBroom]

They can, in unusual instances. This is why doctors quiz you about suicidal ideations whenever you are prescribed a new SSRI.