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The article is quite one-sided. My experience is certainly that B6 has an effect on nerves, but in my case that's been a good thing. I started a software job in 1995, writing a lot of code. By mid-1997, I had severe nerve pain in both wrists, even with ice, stretching, and ibuprofen. I went to an excellent orthopedist who prescribed two things: a Kinesis Advantage keyboard to mostly immobilize the wrists while typing, and 50 mg of Vitamin B6 per day. The combination saved my career. I sometimes get out of the habit of taking the B6 for a week or two, out of sheer forgetfulness. After a couple of weeks, I'll start noticing very minor nerve pain if I'm using the Kinesis Advantage keyboard (I'm typing this on one right now.) But if I'm typing on a normal keyboard at a client site, a week or so is enough to bring back noticeable nerve pain, which reminds me to start the B6 regimen again. After a few days on B6, the pain recedes. I was a little nervous at taking 2500% of the RDA, so I researched the medical literature, and the studies I found showing problems caused by excessive B6 all described people taking 200mg or more per day. The article notes that "since 2022 the TGA has required a warning label for listed medicines with more than 10mg of B6." So maybe studies showing the potential for harm have come out since then; I don't know. On the other hand, has anyone ever gathered data to show whether supplemental B6 actually does improve cases like mine? Vitamin B6 can't be patented, so there's no money to be made, so who is going to fund that study? |
In pregnant adult women, vitamin B6 is likely safe at a dose of up to 100 mg per day. In adolescent pregnancy, vitamin B6 is likely safe at a dose of up to 80 mg per day.
In lactating adult women, vitamin B6 is likely safe at a dose of up to 100 mg per day. In adolescents who are lactating, vitamin B6 is likely safe at a dose of up to 80 mg per day.
In children, vitamin B6 is likely safe at a daily dose of 30 mg (1-3 yrs), 40 mg (4-8 yrs), 60 mg (9-13 yrs) and 80 mg (14-18 yrs).
The likelihood of side effects increases at doses higher than 200 mg per day.
In 2023, the European Food Safety Authority set an upper limit of vitamin B6 of 12 mg per day for adults, and 2.2 to 10.7 mg per day for infants and children.
Source: https://inspectsupplement.com/vitamin-b6 (Edited Note: My Website)