Anyhow still makes things easier for application development. The main drawback is that the resulting error type doesn't implement std::error::Error, so it's not suitable for library development (as pointed out in the anyhow documentation). Stack Error is a bit less ergonomic, but suitable for library development.
I prefer Anyhow's non-intrusiveness: "Result" is still "Result" and all I need is a "?". I agree with Stack Error's documentation that Anyhow can't help with debugging that well, but it's "good enough" in my opinion.