[paulmckeever]

There are quite a few new services emerging that are making designers less dependent on drawing tools:

* Gridset (http://gridsetapp.com) -- for working out your grid and bringing it into a prototype

* Typecast (http://beta.typecastapp.com) -- design with web fonts

* Easel (http://easel.io) -- a browser-based alternative to Fireworks

* CSS Piffle (http://csspiffle.com) -- haven't actually used this yet but looks similar to Easel from the outside

* Adobe Muse (http://www.adobe.com/products/muse.html) -- not well received but maybe an indication of Adobe's future direction

[disclaimer: I'm part of the Typecast team].

Photoshop and Fireworks are great and I don't see many designers abandoning desktop software entirely. But I think there are plenty of tools that can help you get into the browser more quickly.