There is also evidence linking some common pharmaceuticals to long term deficits in memory and cognition.
Diphenhydramine (Benadryl/OTC Sleep Aids) use is associated with an increased risk of dementia [1], while benzodiazepines like Xanax and Ativan are strongly associated with long term cognitive deficits [2]. Taking many drugs is a cost-benefit analysis, and it's important to be informed about the possible consequences before diving in.