[BugsJustFindMe]

Uh...no...

It would be completely bonkers for an antiemetic to commonly induce an emetic urge in any but rare exceptional cases.

Most seasickness drugs are just first-generation antihistamines sometimes combined with a caffeine analogue to counteract the sleepiness.

Dramamine/Gravol (dimenhydrinate) is just benadryl (diphenhydramine) plus the caffeine analogue theophylline.

Bonine/DramamineII (meclizine) is also a first-generation antihistamine.

Promethazine is also a first-generation antihistamine.

Non-antihistamine antiemetics like ondansetron or scopolamine transdermal patches require a prescription from a doctor and therefore aren't commonly used for motion sickness except for occupational seafarers. And it would still be absolutely stupid if the drugs given to prevent nausea commonly caused nausea.

[DrBenCarson]

I think it’s not uncommon for a drug treating some condition with some symptom to have a potential side effect that worsens that symptom. When you start playing with some set of receptors, it’s possible something goes too far or, for whatever reason, not far enough and now we’re worse off

See: antidepressants can increase suicidal ideation, cannabis (used for nausea) can cause nausea at higher doses, etc.

[BugsJustFindMe]

> I think it’s not uncommon for a drug treating some condition with some symptom to have a potential side effect that worsens that symptom.

I think you're making the error of conflating probabilities here. It's not uncommon for drugs to have uncommon side effects, but those side effects are still uncommon. Every once in a while benadryl makes a person paradoxically excited, but most people who take benadryl get sleepy.

[xico]

As an occasional user, can confirm that motion sickness pills (e.g. Cinnarizine, one of the most used in the British Navy) make dizzy, some more than other, and that it’s still much better overall than not taking them.

[rzzzt]

Why would it be stupid? You are concentrating on the vomiting part but aren't other sensations related to motion sickness like shaky balance that drugs could help out with?

[OJFord]

Not to mention the possibility of triggering a response that the trigger would help combat if you already exhibited the response. Or it simply being an uncommon side effect that it's made worse. Headaches and nausea are listed in possible side effects for just about everything, because if anyone reports it they have to list it since the possibility of causality hasn't been ruled out.

[dcow]

Does that mean when death is listed that somebody died during the trial?

[BugsJustFindMe]

> You are concentrating on the vomiting part

The nausea part. The person I'm replying to specifically said "queasy".