I would have assumed the opposite. If you're spreading the weekly dose into daily pills the dosage each time might be small enough to minimise the side effects (nausea etc).
Probably wise to not make any assumptions. It's possible that what you're positing will turn out to be true, but it's also possible that (for example) the presence of the drug in the digestive system before it's absorbed into the blood is the cause of the side effects. Time will tell.