[johnea]

How would they "demand" this?

Large pharma is going to develop in the US, where tax dollars fund a significant portion of research, and they get exclusive ownership of the resulting product.

Single payer systems do still display advantages for the drug's users.

Surely you've heard of people in the US buying prescription meds from Canada?

[ninalanyon]

> How would they "demand" this?

By asking a drug company to develop a therapy for a specific condition and offering to pay for it? Couple that with refusing to pay for drugs that do not offer good value for society as a whole.