[rayiner]

Do you know it works? I’d be curious to know your prior—do you think medical interventions for behavioral problems typically work?

We know, for example, that medical interventions to address obesity typically don’t work (without surgery). https://pmc.ncbi.nlm.nih.gov/articles/PMC8427732/

[xnx]

> We know, for example, that medical interventions to address obesity typically don’t work (without surgery).

This seems like a wild example to use given the runway success of GLP-1 drugs

[rayiner]

Sorry, I’m old and sometimes forget GLP-1 drugs exist now. But that’s kind of my point—those drugs seem like magic because medical interventions for obesity control were so extremely ineffective until just a couple of years ago.

We don’t have anything akin to GLP-1 drugs for opiate addiction, or alcohol addiction, etc.

[xnx]

> We don’t have anything akin to GLP-1 drugs for opiate addiction, or alcohol addiction, etc.

Surprisingly, there's some evidence that GLP-1 drugs may also help with drug and alcohol cravings!

https://www.niaaa.nih.gov/news-events/research-update/semagl...