[pickle-wizard]

I haved looked much into Virtual Cards. Do they have the same BIN as a physical card. There are public lists of BINs. You could grab all the virtual card BINs and block them. Though that would take some maintenance as new ones are added.

Also it is likely that your merchant processor offers this as a service. You should speak with them. Back we I worked for a processor we offered all kinds of different logic on different card types. They are not usually turned on by default and you have to request they be turned on. One that our customers frequently requested was to block pre-paid cards.