|
|
|
|
|
|
by reasonattlm
5067 days ago
|
|
|
The interesting thing about intermittent fasting is that it seems to work through a different but overlapping set of molecular mechanisms to calorie restriction. The gene expression profiles in rodents say that the way in which intermittent fasting (such as alternate day fasting, the most commonly studied mode) works to alter metabolism into a better running state is not quite the same as the mechanisms of straight calorie restriction. http://www.fightaging.org/archives/2010/05/intermittent-fast... http://www.fightaging.org/archives/2009/11/a-little-intermit... So evidently you still have upregulated autophagy (i.e. better housekeeping in cells), the levels of methionine in the diet are going to be lower thus triggering that important switch in the metabolism of calorie restriction, more ghrelin floating around to stimulate the immune system, and so on. But it's not running the same way as for a steady low diet, and that appears to make some differences. Intermittent fasting is not as well studied as calorie restriction, but it is shown to extend life in mammals, and it is certainly easier to manage for most humans: http://www.fightaging.org/archives/2009/02/practicing-interm... Which means to say that you'll probably obtain health benefits by doing it, but the studies that show massive health gains and enormously lowered risk of age-related disease for calorie restricted humans may or may not apply to you. |
|
|