[coopdog]

I think ther are some sexy B2B problems, ie problems that can solved with technology rather than business solutions that use a tiny bit of software.

Analytics is pretty huge. Companies will pay big dollars for profitable insights into their data, queue distributed computing and machine learning. In machine learning and AI there are a massive number tasks being done by unskilled temps that could be automated away, for example data entry, basic research, report interpretation (back to analytics).

Then there's whole field of taking almost any piece of enterprise software and just giving it a decent/usable user experience, using sexy Web tech, html5, etc.

I think the only thing unsexy about b2b is that you'll never be famous in your friends eyes, ie you'll be the guy who made their accounting software 30% less frustrating rather than the guy who created the latest local cat photo montage social network