[kalupa]

It has great support for blocking yes. In fact, there are curated and/or crowdsourced block lists that one can subscribe to so you don’t have to spend as much time doing it yourself. I am sure there’s one that’s suitable for your needs but I don’t have any to recommend

[underseacables]

..you can do that?! I've been dreaming of the ability to block certain words and phrases from Twitter. Blue sky is too chaotic for me… I'm OK sticking with Twitter so long as I can block words and phrases.