[brothrock]

N=1 is addressed, see outcome predictions. N=1 comes with caveats, of course, but a study like this, with a proven harmless supplement, should be welcomed and praised.

It is clearly a step forward from what you can watch about theanine on YouTube or TikTok. I consider this a work of citizen science. While it should not be taken for more than it is, it’s a great example of how someone can experiment without a high burden.

[matthewdgreen]

N=1 studies aren’t evil. They’re just pretty close to the entire history of pre-modern medicine that led us to bad evidence. My concern here is not that someone is sharing their opinions, it’s the fact that the person doing this explicitly heaps derision on the “placebo people” (or some other phrasing) and then heaps praise on other people doing N=1 studies and proceeds to do one. This stuff all needs to be treated with humor, good faith, and then extreme skepticism about any result it produces.

[ryandrake]

That's a pretty low bar though. OK, it's one step up from a monetized YouTube video that boils down to "It works--Trust me, bro." I still wouldn't really call it citizen science.