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by inglor_cz 474 days ago
"The idea that an overweight person has "too much muscle" is nonsense."

Our bodies like to have a balance of everything.

"Muscle mass is a huge predictor of mortality"

In biology, most such predictors work only up to a point. Massively muscular people don't live to be 120. Bodies don't work in a straightforward fashion, and there are other effects to consider. For example, activation of the mTOR pathway, associated with tissue growth, is associated with shorter lifespan, and mTOR inhibitors like rapamycin seem to be modestly prolonging lives of many species.